Different definition of sarcopenia and mortality in cancer: A meta-analysis.

ABSTRACT:

Objectives

Sarcopenia has been an emerging theme in clinical oncology. Various definitions of sarcopenia have been proposed, but their prognostic performance have yet to be evaluated and compared. The aim of this meta-analysis is to comprehensively evaluate the performance of different cutoff definitions of sarcopenia in cancer mortality prognostication.

Methods

This is a meta-analysis. Cohort studies on lean mass and mortality published before December 20, 2017 were obtained by systematic search on PubMed, Cochrane Library, and Embase. Inclusion criteria were cohort studies reporting binary lean mass categorized according to clearly defined cutoffs, and with all-cause mortality as study outcome. Studies were stratified according to the cutoff(s) used in defining low lean ma

SUBMITTER: Li HL 

PROVIDER: S-EPMC8088994 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature