Variability and effect sizes of intracranial current source density estimations during pain: Systematic review, experimental findings, and future perspectives.

ABSTRACT: Pain arises from the integration of sensory and cognitive processes in the brain, resulting in specific patterns of neural oscillations that can be characterized by measuring electrical brain activity. Current source density (CSD) estimation from low-resolution brain electromagnetic tomography (LORETA) and its standardized (sLORETA) and exact (eLORETA) variants, is a common approach to identify the spatiotemporal dynamics of the brain sources in physiological and pathological pain-related conditions. However, there is no consensus on the magnitude and variability of clinically or experimentally relevant effects for CSD estimations. Here, we systematically examined reports of sample size calculations and effect size estimations in all studies that included the keywords pain, and LORETA, sLO

SUBMITTER: Volker JM 

PROVIDER: S-EPMC8090781 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature