Developmental Variation in Amygdala Volumes: Modeling Differences Across Time, Age, and Puberty.

ABSTRACT:

Background

There is evidence that the amygdala undergoes extensive development. The exact nature of this change remains less clear, with evidence suggesting linear, curvilinear, and null effects. The aim of this study was the identification of a normative reference of left and right amygdala development by parceling variance into separate effects of age and longitudinal growth.

Methods

Data came from the National Institutes of Health MRI Study of Normal Brain Development. Participants in this sample were 54% female and ranged in age from 5 to 18 years (mean = 11.37 years) at study entry.

Results

As predicted, the age at initial scan moderated the slope of both left and right amygdala volumes, demonstrating that the nature of longitudinal growth varies across age (i.e.

SUBMITTER: Russell JD 

PROVIDER: S-EPMC8091485 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature