Amoxicillin-Clavulanic Acid Resistance in the Genus Bifidobacterium.

ABSTRACT: Amoxicillin-clavulanic acid (AMC) is one of the most frequently prescribed antibiotic formulations in the Western world. Extensive oral use of this antimicrobial combination influences the gut microbiota. One of the most abundant early colonizers of the human gut microbiota is represented by different taxa of the Bifidobacterium genus, which include many members that are considered to bestow beneficial effects upon their host. In the current study, we investigated the impact of AMC administration on the gut microbiota composition, comparing the gut microbiota of 23 children that had undergone AMC antibiotic therapy to that of 19 children that had not been treated with antibiotics during the preceding 6 months. Moreover, we evaluated AMC sensitivity by MIC test of 261 bifidobacterial

SUBMITTER: Mancabelli L 

PROVIDER: S-EPMC8091617 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature