Association of blood culture with carbapenem use in pyogenic liver abscess: a two-center retrospective study.

ABSTRACT:

Background

Highly empiric use of carbapenem in pyogenic liver abscess (PLA) is widespread problem. However, few studies have examined the association between blood culture and carbapenem use in patients with PLA in China. Thus, we conducted this observational study.

Methods

The data of patients diagnosed with PLA at two comprehensive tertiary care centers from 2014 to 2020 were retrospectively collected. Demographic and clinical data were analyzed, and univariate and multivariate analyses were performed to investigate the association between blood culture and carbapenem use. Subgroup analysis was conducted to explore whether the effect is different in sepsis.

Results

Blood culture was performed in 110 (46.0%) patients, of whom 44 (40.0%) patients had positive results

SUBMITTER: He S 

PROVIDER: S-EPMC8091740 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature