The differences in SARS-CoV and SARS-CoV-2 specific co-expression network mediated biological process in human gut enterocytes.

ABSTRACT: Novel coronavirus SARS-CoV-2 was recently outbreak worldwide causes severe acute respiratory syndrome along with gastrointestinal symptoms for some infected patients. Information on detail pathogenesis, host immune responses and responsible biological pathways are limited. Therefore, infection specific host gut responses and dietary supplements to neutralize immune inflammation demand extensive research. This study aimed to find differences in global co-expression protein-protein interaction sub-network and enriched biological processes in SARS-CoV and SARS-CoV-2 infected gut enterocytes cell line. Attempts have also been made to predict some dietary supplements to boost human health. The SARS-CoV and SARS-CoV-2 infected differential express proteins were integrated with the human protein

SUBMITTER: Nayak T 

PROVIDER: S-EPMC8091811 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature