Thrombophilia testing in the real-world clinical setting of thrombosis centres taking part in the Italian Start 2-Register.

ABSTRACT:

Background

Even though it rarely influences venous thromboembolism (VTE) treatment and the fact that it is generally discouraged, thrombophilia testing is still largely prescribed. We assessed: 1) whether/how frequently Italian thrombosis centres requested thrombophilia testing; 2) what results were obtained; and 3) if the results affected treatment and clinical results.

Materials and methods

We examined data from 4,826 VTE patients enrolled by 19 clinical centres participating in the START 2-Register.

Results

57.2% of patients were tested. Numbers varied widely among centres (2.9-99.7%). Thrombophilic alterations were recorded in 18.2% of patients and the percentage of positive results was inversely correlated with that of patients tested. Significantly less patients

SUBMITTER: Legnani C 

PROVIDER: S-EPMC8092043 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature