Heart Failure Hospitalization Risk associated with Iron Status in Veterans with CKD.

ABSTRACT:

Background and objectives

CKD is an independent risk factor for heart failure. Iron dysmetabolism potentially contributes to heart failure, but this relationship has not been well characterized in CKD.

Design, setting, participants, & measurements

We performed a historical cohort study using data from the Veterans Affairs Corporate Data Warehouse to evaluate the relationship between iron status and heart failure hospitalization. We identified a CKD cohort with at least one set of iron indices between 2006 and 2015. The first available date of serum iron indices was identified as the study index date. The cohort was divided into four iron groups on the basis of the joint quartiles of serum transferrin saturation (shown in percent) and ferritin (shown in nanograms per millilit

SUBMITTER: Cho ME 

PROVIDER: S-EPMC8092060 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature