Multigene tests for breast cancer: the physician's perspective.

ABSTRACT: Breast cancer is the most common tumour in women and the first cause of death for cancer in the female population. Preserving the quality of life has therefore become an important objective in the management of the disease. The benefits of adjuvant chemotherapy in patients with HR+ HER2- early breast cancer should always be balanced against its potential short and long-term adverse effects, and identifying the appropriate patients for whom chemotherapy can offer the highest clinical benefit is critical. Besides clinical and pathological factors, today four multigene tests able to guide the choice of the adjuvant therapy early breast cancer are available in Italy: Oncotype DX^®, EndoPredict^®, MammaPrint^® e Prosigna^®. This review evaluates the main

SUBMITTER: Cognetti F 

PROVIDER: S-EPMC8092339 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature