Antagonistic activities of cotranscriptional regulators within an early developmental window set <i>FLC</i> expression level.

ABSTRACT: Quantitative variation in expression of the Arabidopsis floral repressor FLC influences whether plants overwinter before flowering, or have a rapid cycling habit enabling multiple generations a year. Genetic analysis has identified activators and repressors of FLC expression but how they interact to set expression level is poorly understood. Here, we show that antagonistic functions of the FLC activator FRIGIDA (FRI) and the repressor FCA, at a specific stage of embryo development, determine FLC expression and flowering. FRI antagonizes an FCA-induced proximal polyadenylation to increase FLC expression and delay flowering. Sector analysis shows that FRI activity during the early heart stage of embryo development maximally delays flowering. Opposing

SUBMITTER: Schon M 

PROVIDER: S-EPMC8092400 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature