Hemodynamic and Non-Hemodynamic Components of Cardiac Remodeling in Primary Aldosteronism.

ABSTRACT:

Objectives

Patients with primary aldosteronism (PA) have cardiac remodeling due to hemodynamic and non-hemodynamic causes. However, component analysis of cardiac remodeling and reversal in PA patients is lacking. We investigated components of cardiac remodeling and reversal after adrenalectomy in patients with aldosterone-producing adenoma (APA).

Methods

This study prospectively enrolled 304 APA patients who received adrenalectomy and 271 with essential hypertension (EH). Clinical, biochemical and echocardiographic data were collected in both groups and 1 year after surgery in the APA patients. The hemodynamic and non-hemodynamic components of left ventricular (LV) remodeling were represented by predicted left ventricular mass index (LVMI) (pLVMI) and inappropriately excessi

SUBMITTER: Pan CT 

PROVIDER: S-EPMC8092478 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature