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Allografts and Spinal Fusion.


ABSTRACT:

Background

Back pain is a common chief complaint within the United States and is caused by a multitude of etiologies. There are many different treatment modalities for back pain, with a frequent option being spinal fusion procedures. The success of spinal fusion greatly depends on instrumentation, construct design, and bone grafts used in surgery. Bone allografts are important for both structural integrity and providing a scaffold for bone fusion to occur.

Method

Searches were performed using terms "allografts" and "bone" as well as product names in peer reviewed literature Pubmed, Google Scholar, FDA-510k approvals, and clinicaltrials.gov.

Results

This study is a review of allografts and focuses on currently available products and their success in both animal and clinical studies.

Conclusion

Bone grafts used in surgery are generally categorized into 3 main types: autogenous (from patient's own body), allograft (from cadaveric or living donor), and synthetic. This paper focuses on allografts and provides an overview on the different subtypes with an emphasis on recent product development and uses in spinal fusion surgery.

SUBMITTER: Cohen JD 

PROVIDER: S-EPMC8092936 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature

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Allografts and Spinal Fusion.

Cohen Justin D JD   Kanim Linda E LE   Tronits Andrew J AJ   Bae Hyun W HW  

International journal of spine surgery 20210421 s1


<h4>Background</h4>Back pain is a common chief complaint within the United States and is caused by a multitude of etiologies. There are many different treatment modalities for back pain, with a frequent option being spinal fusion procedures. The success of spinal fusion greatly depends on instrumentation, construct design, and bone grafts used in surgery. Bone allografts are important for both structural integrity and providing a scaffold for bone fusion to occur.<h4>Method</h4>Searches were per  ...[more]

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