Cognitive performance as a predictor of healthcare transition in sickle cell disease.

ABSTRACT: Neurocognitive deficits in sickle cell disease (SCD) may impair adult care engagement. We investigated the relationship between neurocognitive functioning and socio-environmental factors with healthcare transition outcomes. Adolescents aged 15-18 years who had neurocognitive testing and completed a visit with an adult provider were included. Transition outcomes included transfer interval from paediatric to adult care and retention in adult care at 12 and 24 months. Eighty adolescents (59% male, 64% HbSS/HbSβ⁰ -thalassaemia) were included. Mean age at adult care transfer was 18·0 (±0·3) years and transfer interval was 2·0 (±2·3) months. Higher IQ (P = 0·02; P_FDR  = 0·05) and higher verbal comprehension (P = 0·008; P_FDR  = 0·024) were associated with <2 and <

SUBMITTER: Saulsberry-Abate AC 

PROVIDER: S-EPMC8092972 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature