Rich-club structure contributes to individual variance of reading skills via feeder connections in children with reading disabilities.

ABSTRACT: The present work considers how connectome-wide differences in brain organization might distinguish good and poor readers. The connectome comprises a 'rich-club' organization in which a small number of hub regions play a focal role in assisting global communication across the whole brain. Prior work indicates that this rich-club structure is associated with typical and impaired cognitive function although no work so far has examined how this relates to skilled reading or its disorders. Here we investigated the rich-club structure of brain's white matter connectome and its relationship to reading subskills in 64 children with and without reading disabilities. Among three types of white matter connections, the strength of feeder connections that connect hub and non-hub nodes was significantly

SUBMITTER: Lou C 

PROVIDER: S-EPMC8093404 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature