Evaluation of the effectiveness and safety of adding ivermectin to treatment in severe COVID-19 patients.

ABSTRACT:

Background and objectives

An effective treatment option is not yet available for SARS-CoV2, which causes the COVID-19 pandemic and whose effects are felt more and more every day. Ivermectin is among the drugs whose effectiveness in treatment has been investigated. In this study; it was aimed to investigate the presence of gene mutations that alter ivermectin metabolism and cause toxic effects in patients with severe COVID-19 pneumonia, and to evaluate the effectiveness and safety of ivermectin use in the treatment of patients without mutation.

Materials and methods

Patients with severe COVID19 pneumonia were included in the study, which was planned as a prospective, randomized, controlled, single-blind phase 3 study. Two groups, the study group and the control group, took pa

SUBMITTER: Okumus N 

PROVIDER: S-EPMC8093585 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature