A Prognostic Model Based on the Immune-Related lncRNAs in Colorectal Cancer.

ABSTRACT:

Background

Colorectal cancer (CRC) is one of the most common malignant tumors with a poor prognosis. At present, the pathogenesis is not completely clear. Therefore, finding reliable prognostic indicators for CRC is of important clinical significance. In this study, bioinformatics methods were used to screen the prognostic immune-related lncRNAs of CRC, and a prognostic risk scoring model based on immune-related lncRNAs signatures were constructed to provide a basis for prognostic evaluation and immunotherapy of CRC patients.

Methods

The clinical information and RNA-seq data of CRC patients were obtained from The Cancer Genome Atlas (TCGA) database. The information of immune-related lncRNA was downloaded from the immunology database and analysis portal. The differentially ex

SUBMITTER: Qin F 

PROVIDER: S-EPMC8093825 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature