Association of Lumbar Puncture With Spinal Hematoma in Patients With and Without Coagulopathy.

ABSTRACT:

Importance

Coagulopathy may deter physicians from performing a lumbar puncture.

Objective

To determine the risk of spinal hematoma after lumbar puncture in patients with and without coagulopathy.

Design, setting, and participants

Danish nationwide, population-based cohort study using medical registries to identify persons who underwent lumbar puncture and had cerebrospinal fluid analysis (January 1, 2008-December 31, 2018; followed up through October 30, 2019). Coagulopathy was defined as platelets lower than 150 × 109/L, international normalized ratio (INR) greater than 1.4, or activated partial thromboplastin time (APTT) longer than 39 seconds.

Exposures

Coagulopathy at the time of lumbar puncture.

Main outcomes and measures

Thirty-day risk of spinal h

SUBMITTER: Bodilsen J 

PROVIDER: S-EPMC8094417 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature