DM3Loc: multi-label mRNA subcellular localization prediction and analysis based on multi-head self-attention mechanism.

ABSTRACT: Subcellular localization of messenger RNAs (mRNAs), as a prevalent mechanism, gives precise and efficient control for the translation process. There is mounting evidence for the important roles of this process in a variety of cellular events. Computational methods for mRNA subcellular localization prediction provide a useful approach for studying mRNA functions. However, few computational methods were designed for mRNA subcellular localization prediction and their performance have room for improvement. Especially, there is still no available tool to predict for mRNAs that have multiple localization annotations. In this paper, we propose a multi-head self-attention method, DM3Loc, for multi-label mRNA subcellular localization prediction. Evaluation results show that DM3Loc outperforms exist

SUBMITTER: Wang D 

PROVIDER: S-EPMC8096227 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature