Functional Connectivity of the Human Paraventricular Thalamic Nucleus: Insights From High Field Functional MRI.

ABSTRACT: The paraventricular thalamic nucleus (PVT) is a small but highly connected nucleus of the dorsal midline thalamus. The PVT has garnered recent attention as a context-sensitive node within the thalamocortical arousal system that modulates state-dependent motivated behaviors. Once considered related to generalized arousal responses with non-specific impacts on behavior, accumulating evidence bolsters the contemporary view that discrete midline thalamic subnuclei belong to specialized corticolimbic and corticostriatal circuits related to attention, emotions, and cognition. However, the functional connectivity patterns of the human PVT have yet to be mapped. Here, we combined high-quality, high-resolution 7T and 3T resting state MRI data from 121 young adult participants from the Human Connect

SUBMITTER: Kark SM 

PROVIDER: S-EPMC8096909 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature