Ontology highlight
ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC8097267 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Wang Yaguo Y Li Zihui Z Wu Shucai S Fleming Joy J Li Chuanyou C Zhu Guofeng G Chen Bo B Ren Baiguang B Wang Xingyun X Du Boping B Li Pingjun P Hu Peilei P Yang Juwang J Liu Yi Y Zhou Chongchen C Zhang Xian-En XE Bi Lijun L Zhang Hongtai H Yang Junmei J Zhang Zongde Z
Infection and immunity 20210216 3
The lack of efficacious vaccines against <i>Mycobacterium tuberculosis</i> (MTB) infection is a limiting factor in the prevention and control of tuberculosis (TB), the leading cause of death from an infectious agent. Improvement or replacement of the BCG vaccine with one that reliably protects all age groups is urgent. Concerns exist that antigens currently being evaluated are too homogeneous. To identify new protective antigens, we screened 1,781 proteins from a high-throughput proteome-wide pr ...[more]