Integrating Linguistics, Social Structure, and Geography to Model Genetic Diversity within India.

ABSTRACT: India represents an intricate tapestry of population substructure shaped by geography, language, culture, and social stratification. Although geography closely correlates with genetic structure in other parts of the world, the strict endogamy imposed by the Indian caste system and the large number of spoken languages add further levels of complexity to understand Indian population structure. To date, no study has attempted to model and evaluate how these factors have interacted to shape the patterns of genetic diversity within India. We merged all publicly available data from the Indian subcontinent into a data set of 891 individuals from 90 well-defined groups. Bringing together geography, genetics, and demographic factors, we developed Correlation Optimization of Genetics and Geodemograp

SUBMITTER: Bose A 

PROVIDER: S-EPMC8097304 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature