Closed incision negative pressure wound therapy versus standard dressings in obese women undergoing caesarean section: multicentre parallel group randomised controlled trial.

ABSTRACT:

Objective

To determine the effectiveness of closed incision negative pressure wound therapy (NPWT) compared with standard dressings in preventing surgical site infection (SSI) in obese women undergoing caesarean section.

Design

Multicentre, pragmatic, randomised, controlled, parallel group, superiority trial.

Setting

Four Australian tertiary hospitals between October 2015 and November 2019.

Participants

Eligible women had a pre-pregnancy body mass index of 30 or greater and gave birth by elective or semi-urgent caesarean section.

Intervention

2035 consenting women were randomised before the caesarean procedure to closed incision NPWT (n=1017) or standard dressing (n=1018). Allocation was concealed until skin closure.

Main outcome measures

The prim

SUBMITTER: Gillespie BM 

PROVIDER: S-EPMC8097312 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature