Application of the adverse outcome pathway framework to predict the toxicity of chemicals in the semiconductor manufacturing industry.

ABSTRACT:

Background

To solve current issues using big data, solve current issues related to the semiconductor and electronics industry, I tried to establish the data for each toxicity mechanism for adverse outcome pathway (AOP) for the exposure.

Objective

I planned to increase the efficiency of human hazard assessment by searching, analyzing, and linking test data on the relationship between key events occurred at each level, which are the biological targets of chemicals in semiconductor manufacturing.

Results

It was found that 48 kinds of chemicals had 11 AOPs, while 103 chemicals had multiple AOPs, and 26 had case evidence. As a result of AOP analysis, it was found that a total of 320 chemicals had 42 AOPs, and 190 major chemicals corresponded to 11 AOPs. It was found necess

SUBMITTER: Rim KT 

PROVIDER: S-EPMC8097676 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature