Molecular-genetic characterization of human parvovirus B19 prevalent in Kerala State, India.

ABSTRACT:

Background

Human parvovirus B19V is a DNA virus, and a member of the family Parvoviridae, that causes various clinical manifestations, from asymptomatic to persistent infection that is associated with different autoimmune diseases. The parvovirus B19 evolves with a very high mutation rate that is closer to those of existing RNA viruses. Globally circulating B19V is currently classified into three genotypes, but their distribution is not spatially and temporally correlated. Except for a few recent reports on B19V entry into the human host and its genetic diversity, there is a lack of sufficient studies on this virus from distinct geographical locations and no clear understanding of its evolution has been documented.

Methods

To better understand the evolution of the Human parv

SUBMITTER: Seetha D 

PROVIDER: S-EPMC8097873 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature