Functional connectivity changes in cerebral small vessel disease - a systematic review of the resting-state MRI literature.

ABSTRACT:

Background

Cerebral small vessel disease (CSVD) is a common neurological disease present in the ageing population that is associated with an increased risk of dementia and stroke. Damage to white matter tracts compromises the substrate for interneuronal connectivity. Analysing resting-state functional magnetic resonance imaging (fMRI) can reveal dysfunctional patterns of brain connectivity and contribute to explaining the pathophysiology of clinical phenotypes in CSVD.

Materials and methods

This systematic review provides an overview of methods and results of recent resting-state functional MRI studies in patients with CSVD. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) protocol, a systematic search of the literature was performed.

SUBMITTER: Schulz M 

PROVIDER: S-EPMC8097883 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature