Studies of Dynamic Binding of Amino Acids to TiO₂ Nanoparticle Surfaces by Solution NMR and Molecular Dynamics Simulations.

ABSTRACT: Adsorption of biomolecules onto material surfaces involves a potentially complex mechanism where molecular species interact to varying degrees with a heterogeneous material surface. Surface adsorption studies by atomic force microscopy, sum frequency generation spectroscopy, and solid-state NMR detect the structures and interactions of biomolecular species that are bound to material surfaces, which, in the absence of a solid-liquid interface, do not exchange rapidly between surface-bound forms and free molecular species in bulk solution. Solution NMR has the potential to complement these techniques by detecting and studying transiently bound biomolecules at the liquid-solid interface. Herein, we show that dark-state exchange saturation transfer (DEST) NMR experiments on gel-stabilized TiO<

SUBMITTER: Xue M 

PROVIDER: S-EPMC8098425 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature