Spatiotemporal distribution of cutaneous leishmaniasis in Sri Lanka and future case burden estimates.

ABSTRACT:

Background

Leishmaniasis is a neglected tropical vector-borne disease, which is on the rise in Sri Lanka. Spatiotemporal and risk factor analyses are useful for understanding transmission dynamics, spatial clustering and predicting future disease distribution and trends to facilitate effective infection control.

Methods

The nationwide clinically confirmed cutaneous leishmaniasis and climatic data were collected from 2001 to 2019. Hierarchical clustering and spatiotemporal cross-correlation analysis were used to measure the region-wide and local (between neighboring districts) synchrony of transmission. A mixed spatiotemporal regression-autoregression model was built to study the effects of climatic, neighboring-district dispersal, and infection carryover variables on leishma

SUBMITTER: Karunaweera ND 

PROVIDER: S-EPMC8099137 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature