Relative light sensitivities of four retinal hemi-fields for suppressing the synthesis of melatonin at night.

ABSTRACT: The magnitude of the stimulus to the biological clock will depend upon the distribution of circadian phototransduction circuits across the retinae and the spatial distribution of luminous stimuli in the environment. The present study compared nocturnal melatonin suppression for light exposures to the superior, inferior, nasal, and temporal retina in one eye independent of shading from the brow and the nose. The stimulus was a 40° diameter luminous disc, half of which was blue light (LED, λ_peak = 470 nm) and the other amber light (LED, λ_peak = 590 nm). Experimentally, the orientation of the bipartite disc was rotated to each of the four cardinal points of the visual field. A full, 40° blue disc was also employed by replacing the amber half-disc with another blue half-d

SUBMITTER: Rea MS 

PROVIDER: S-EPMC8099627 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature