Time-Restricted Feeding Regulates Circadian Rhythm of Murine Uterine Clock.

ABSTRACT:

Background

Skipping breakfast is associated with dysmenorrhea in young women. This suggests that the delay of food intake in the active phase impairs uterine functions by interfering with circadian rhythms.

Objectives

To examine the relation between the delay of feeding and uterine circadian rhythms, we investigated the effects of the first meal occasion in the active phase on the uterine clock.

Methods

Zeitgeber time (ZT) was defined as ZT0 (08:45) with lights on and ZT12 (20:45) with lights off. Young female mice (8 wk of age) were divided into 3 groups: group I (ad libitum consumption), group II (time-restricted feeding during ZT12-16, initial 4 h of the active period), and group III (time-restricted feeding during ZT20-24, last 4 h of the active period, a breakfas

SUBMITTER: Hosono T 

PROVIDER: S-EPMC8099714 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature