All-Cause and Cardiovascular Mortality Among Insulin-Naive People With Type 2 Diabetes Treated With Insulin Detemir or Glargine: A Cohort Study in the UK.

ABSTRACT:

Introduction

Uncontrolled type 2 diabetes (T2D) is associated with an increased risk of micro- and macrovascular complications and mortality. The impact of basal insulins on the risks of mortality and cardiovascular mortality in people with T2D has not been thoroughly investigated in real-world settings. The aim of the present real-word study was to investigate differences in mortality among insulin-naïve people with T2D who initiated insulin detemir (detemir) and insulin glargine (glargine).

Methods

We assessed all-cause and cardiovascular mortality in people with T2D, aged ≥ 40 years and insulin-naïve at treatment initiation. People were identified from the United Kingdom Clinical Practice Research Datalink GOLD national database (2004-2019). Database information included

SUBMITTER: Husemoen LLN 

PROVIDER: S-EPMC8099979 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature