A network analysis of crab metamorphosis and the hypothesis of development as a process of unfolding of an intensive complexity.

ABSTRACT: Development has intrigued humanity since ancient times. Today, the main paradigm in developmental biology and evolutionary developmental biology (evo-devo) is the genetic program, in which development is explained by the interplay and interaction of genes, that is, by the action of gene regulatory networks (GRNs). However, it is not even clear that a GRN, no matter how complex, can be translated into a form. Therefore, the fundamental enigma of development still remains: how is a complex organism formed from a single cell? This question unfolded the historical drama and the dialectical tension between preformation and epigenesis. In order to shed light on these issues, I studied the development of crabs (infraorder Brachyura), as representative of the subphylum Crustacea, using network the

SUBMITTER: Ostachuk A 

PROVIDER: S-EPMC8100167 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature