A narrative review of urinary phospholipids: from biochemical aspect towards clinical application.

ABSTRACT: As a newly emerged discipline, lipidomic studies have focused on the comprehensive characterization and quantification of lipids in a given biological system, which has remarkably advanced in recent years owing to the rapid development of analytical techniques, especially mass spectrometry. Among diverse lipid classes, phospholipids, which have fundamental roles in the formation of cellular membranes, signaling processes, and bioenergetics have gained momentum in several fields of research. The altered composition, concentration, spatial distribution, and metabolism of phospholipids in cells, tissues, and body fluids have been elucidated in various human diseases such as cancer, inflammation, as well as cardiovascular and metabolic disorders. Among the different kinds of phospholipid sourc

SUBMITTER: Li X 

PROVIDER: S-EPMC8100843 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature