Injectable, self-healing mesoporous silica nanocomposite hydrogels with improved mechanical properties.

ABSTRACT: Self-healing hydrogels have emerged as promising biomaterials in regenerative medicine applications. However, an ongoing challenge is to create hydrogels that combine rapid self-healing with high mechanical strength to make them applicable to a wider range of organs/tissues. Incorporating nanoparticles within hydrogels is a popular strategy to improve the mechanical properties as well as to provide additional functionalities such as stimuli responsiveness or controlled drug delivery, further optimizing their use. In this context, mesoporous silica nanoparticles (MSNs) are promising candidates as they are bioactive, improve mechanical properties, and can controllably release various types of cargo. While commonly nanoparticles are added to hydrogels as filler component, in the current study

SUBMITTER: Zengin A 

PROVIDER: S-EPMC8100892 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature