Evaluation of Topical Corticosteroid Use in Pregnancy and Risk of Newborns Being Small for Gestational Age and Having Low Birth Weight.

ABSTRACT:

Importance

Topical corticosteroids are frequently used during pregnancy. Limited data have raised concerns about an increased risk of the newborn being small for gestational age (SGA) and having low birth weight, in particular with use of potent to very potent agents during pregnancy.

Objective

To evaluate whether topical corticosteroid use in pregnancy is associated with increased risks of SGA and low birth weight.

Design, setting, and participants

From a source cohort of 1.1 million pregnancies with individual-level informed data from various registries, this nationwide cohort study identified topical corticosteroid-exposed pregnancies in Denmark from January 1, 1997, to December 31, 2016, for a total of 60 497, that were matched with 241 986 unexposed pregnancies o

SUBMITTER: Andersson NW 

PROVIDER: S-EPMC8100914 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature