The protective role of serum uric acid against premature membrane rupture in gestational diabetes: a cross-sectional study.

ABSTRACT:

Background

Uric acid has strong antioxidant activity, whereas its oxidative damage is closely related to many diseases. We assessed the association between serum uric acid (SUA) levels and premature rupture of membranes (PROM) in pregnant women with gestational diabetes (GDM) in China.

Methods

In this cross-sectional study, a total of 456 pregnant women were enrolled. Anthropometric parameters for pregnant women were collected within 12 weeks of gestation. Weight gain during pregnancy was obtained from the patients' records. GDM was diagnosed according to 75-g oral glucose tolerance tests at the 24-28th week of gestation, and SUA was determined simultaneously. PROM was identified as the natural rupture of foetal membranes before the first stage of labour. Logistic models wer

SUBMITTER: Guo M 

PROVIDER: S-EPMC8101033 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature