The description of a method for accurately estimating creatinine clearance in acute kidney injury.

ABSTRACT:

Background

Acute kidney injury (AKI) is a common and serious condition encountered in hospitalized patients. The severity of kidney injury is defined by the RIFLE, AKIN, and KDIGO criteria which attempt to establish the degree of renal impairment. The KDIGO guidelines state that the creatinine clearance should be measured whenever possible in AKI and that the serum creatinine concentration and creatinine clearance remain the best clinical indicators of renal function. Neither the RIFLE, AKIN, nor KDIGO criteria estimate actual creatinine clearance. Furthermore there are no accepted methods for accurately estimating creatinine clearance (K) in AKI.

Study design

The present study describes a unique method for estimating K in AKI using urine creatinine excretion over an establi

SUBMITTER: Mellas J 

PROVIDER: S-EPMC8101066 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature