Can perioperative hemodilution be monitored with non-invasive measurement of blood hemoglobin?

ABSTRACT:

Background

Trends in non-invasive measurements of blood hemoglobin (Hb) may be useful for identifying the need for transfusion in the perioperative period.

Methods

Crystalloid fluid (5-20 mL/kg) was administered intravenously or by mouth to 30 volunteers and 33 surgical patients in five non-randomized clinical studies where Hb was measured on 915 occasions by non-invasive (Radical-7™) and invasive methodology. The hemodilution curves were compared by volume kinetic analysis and linear regression, with the slope and scattering of the data as key outcome measures.

Results

The slope was 1.0, indicating unity between the two modes of measuring Hb when crystalloid fluid was infused in volunteers; however, only 40-45% of the variability in the non-invasive Hb could be expla

SUBMITTER: Hahn RG 

PROVIDER: S-EPMC8101100 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature