Clinical and laboratory prognosticators of atrophic papulosis (Degos disease): a systematic review.

ABSTRACT:

Background

Degos disease is a rare vascular disorder with a cutaneous-limited form, benign atrophic papulosis (BAP), and a systemic variant, malignant atrophic papulosis (MAP). Despite the poor prognosis of MAP, no study has established features associated with systemic disease.

Objectives

The aims of this systematic review were to: (1) summarize clinical features and treatments implemented for patients with MAP and BAP (2) identify clinical and laboratory factors associated with the development of MAP, compared to BAP.

Methods

We systematically searched MEDLINE and Embase from inception to April 2020. Demographic and clinical features of Degos patients were presented descriptively; multivariable logistic regression was performed to identify associations with MAP.

SUBMITTER: Lu JD 

PROVIDER: S-EPMC8101154 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature