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The effects of topical erythropoietin on non-surgical treatment of periodontitis: a preliminary study.


ABSTRACT:

Background

The purpose of periodontal treatments is to reduce inflammation, restore gingival health and clinical attachment level gain by controlling microbial plaque formation and other etiological factors. One of the drugs that has been tested in many areas and shown good anti-inflammatory properties is erythropoietin (EPO). We evaluated the effect of this drug on the improvement of periodontitis after the phase I treatment.

Methods

This study was conducted on 30 patients with stage III periodontitis who had at least two bilateral teeth with CAL of ≥ 5 mm and PPD ≥ 6 mm at ≥ 2 non-adjacent teeth and bleeding on probing. After oral hygiene instruction and scaling and root planning (SRP), EPO gel containing a solution of 4000 units was applied deeply in the test group and pl

SUBMITTER: Aslroosta H 

PROVIDER: S-EPMC8101234 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature