Prolonged antibiotic prophylaxis use in elective orthopaedic surgery - a cross-sectional analysis.

ABSTRACT:

Purpose

Surgical antibiotic prophylaxis (SAP) prevents surgical site infections (SSI). In orthopaedic surgery, the use of prolonged SAP (PSAP) has been reported in daily routine, despite guidelines advising against it. Therefore, we asked: What is the proportion of PSAP use, defined as administration of SAP ≥24 h after elective orthopaedic surgery? Are there patient- and surgery-related predictors of PSAP use?

Methods

This cross-sectional analysis investigated 1292 patients who underwent elective orthopaedic surgery including total joint arthroplasties at one Swiss centre between 2015 and 2017. Patient comorbidities, surgical characteristics and occurrence of SSI at 90 days in PSAP group were compared to the SAP group (< 24 h post-operative).

Results

PSAP use was 12%

SUBMITTER: Rohrer F 

PROVIDER: S-EPMC8101240 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature