An Analysis of the Potential Relationship of Triglyceride Glucose and Body Mass Index With Stroke Prognosis.

ABSTRACT: Background: The inverse association between obesity and outcome in stroke patients (known as the obesity paradox) has been widely reported, yet mechanistic details explaining the paradox are limited. The triglyceride glucose (TYG) index has been proposed as a marker of insulin resistance. We sought to explore possible associations of the TYG index, body mass index (BMI), and stroke outcome. Methods: We identified 12,964 ischemic stroke patients without a history of diabetes mellitus from the China National Stroke Registry and classified patients as either low/normal weight, defined as a BMI <25 kg/m², or overweight/obese, defined as a BMI ≥ 25 kg/m². We calculated TYG index and based on which the patients were divided into four groups. A Cox or logistic

SUBMITTER: Hou Z 

PROVIDER: S-EPMC8101495 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature