Unknown

Dataset Information

0

EZH2 inactivation in RAS-driven myeloid neoplasms hyperactivates RAS-signaling and increases MEK inhibitor sensitivity.

ABSTRACT:

SUBMITTER: Berg JL 

PROVIDER: S-EPMC8102185 | biostudies-literature |

REPOSITORIES: biostudies-literature

Json Xml

Similar Datasets

Unknown Sensitivity and Resistance of Oncogenic RAS-Driven Tumors to Dual MEK and ERK Inhibition.
| S-EPMC8069437 | biostudies-literature
Unknown Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms.
| S-EPMC6436863 | biostudies-literature
Unknown Antitumor activity in RAS-driven tumors by blocking AKT and MEK.
| S-EPMC4335074 | biostudies-literature
Unknown MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma.
| S-EPMC8054766 | biostudies-literature
Unknown Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model.
| S-EPMC5833851 | biostudies-literature
Unknown Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers.
| S-EPMC6918830 | biostudies-literature
Unknown Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma.
| S-EPMC5415387 | biostudies-literature
Transcriptomics Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition
2018-04-01 | GSE85171 | GEO
Unknown Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110α.
| S-EPMC3973083 | biostudies-literature
Unknown Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis.
| S-EPMC3938162 | biostudies-literature