Cancer Risk in Normal Weight Individuals with Metabolic Obesity: A Narrative Review.

ABSTRACT: Obesity represents one of the most significant public health challenges worldwide. Current clinical practice relies on body mass index (BMI) to define the obesity status of an individual, even though the index has long been recognized for its limitations as a measure of body fat. In normal BMI individuals, increased central adiposity has been associated with worse health outcomes, including increased risks of cardiovascular disease and metabolic disorders. The condition leading to these outcomes has been described as metabolic obesity in the normal weight (MONW). More recent evidence suggests that MONW is associated with increased risk of several obesity-related malignancies, including postmenopausal breast, endometrial, colorectal, and liver cancers. In MONW patients, the false reassuranc

SUBMITTER: Liu B 

PROVIDER: S-EPMC8102335 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature