The Neurotransmitter Receptor Architecture of the Mouse Olfactory System.

ABSTRACT: The uptake, transmission and processing of sensory olfactory information is modulated by inhibitory and excitatory receptors in the olfactory system. Previous studies have focused on the function of individual receptors in distinct brain areas, but the receptor architecture of the whole system remains unclear. Here, we analyzed the receptor profiles of the whole olfactory system of adult male mice. We examined the distribution patterns of glutamatergic (AMPA, kainate, mGlu_2/3, and NMDA), GABAergic (GABA_A, GABA_A(BZ), and GABA_B), dopaminergic (D_1/5) and noradrenergic (α₁ and α₂) neurotransmitter receptors by quantitative in vitro receptor autoradiography combined with an analysis of the cyto- and myelo-archit

SUBMITTER: Lothmann K 

PROVIDER: S-EPMC8102831 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature