The association between insulin sensitivity indices, ECG findings and mortality: a 40-year cohort study.

ABSTRACT:

Background

Type 2 Diabetes is a major risk factor for cardiovascular (CV) mortality. Insulin resistance can be evaluated non-invasively by insulin sensitivity indices (ISI) such as the Mcauley index (MCAi), which is a function of the fasting insulin and triglycerides. Currently, the association between ISIs and ECG findings and all-cause and CV mortality is still not established in a large scale and heterogeneous population.

Method

In a prospective study of the Israel cohort on Glucose Intolerance, Obesity and Hypertension (GOH) second phase (1979-1982) 1830 men and women were followed until December-2016 for CV-mortality and December-2019 for all-cause mortality. ECGs were recorded and OGTTs performed during baseline. ISIs were categorized into quartiles and evaluated again

SUBMITTER: Moshkovits Y 

PROVIDER: S-EPMC8103608 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature