Topical emollient for preventing infection in preterm infants.

ABSTRACT:

Background

Breakdown of the developmentally immature epidermal barrier may permit entry for micro-organisms leading to invasive infection in preterm infants. Topical emollients may improve skin integrity and barrier function and thereby prevent invasive infection, a major cause of mortality and morbidity in preterm infants.

Objectives

To assess the effect of topical application of emollients (ointments, creams, or oils) on the risk of invasive infection and mortality in preterm infants.

Search methods

We searched CENTRAL via Cochrane Register of Studies (CRS) Web and MEDLINE via Ovid (updated 08 January 2021) and the reference lists of retrieved articles.

Selection criteria

Randomised or quasi-randomised controlled trials that assessed the effect of prophylacti

SUBMITTER: Cleminson J 

PROVIDER: S-EPMC8104155 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature