The impact of portal vein tumor thrombosis on survival in patients with hepatocellular carcinoma treated with different therapies: A cohort study.

ABSTRACT:

Background

Portal vein tumor thrombosis (PVTT) is a frequent complication of hepatocellular carcinoma (HCC), which leads to classification as advanced stage disease (regardless of the degree of PVTT) according to the Barcelona Clinic Liver Cancer Classification. For such patients, systemic therapy is the standard of care. However, in clinical reality, many patients with PVTT undergo different treatments, such as resection, transarterial chemoembolization (TACE), selective internal radiation therapy (SIRT), or best supportive care (BSC). Here we examined whether patients benefited from such alternative therapies, according to the extent of PVTT.

Methods

This analysis included therapy-naïve patients with HCC and PVTT treated between January 2005 and December 2016. PVTT was cla

SUBMITTER: Mahringer-Kunz A 

PROVIDER: S-EPMC8104403 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature