Increased risk of secondary lung cancer in patients with tuberculosis: A nationwide, population-based cohort study.

ABSTRACT:

Background

Tuberculosis (TB) presents a global threat in the world and the lung is the frequent site of metastatic focus. A previous study demonstrated that TB might increase primary lung cancer risk by two-fold for more than 20 years after the TB diagnosis. However, no large-scale study has evaluated the risk of TB and secondary lung cancer. Thus, we evaluated the risk of secondary lung cancer in patients with or without tuberculosis (TB) using a nationwide population-based dataset.

Methods

In a cohort study of 1,936,512 individuals, we selected 6934 patients among patients with primary cancer and TB infection, based on the International Classification of Disease (ICD-p-CM) codes 010-011 from 2000 to 2015. The control cohort comprised 13,868 randomly selected, propensity-ma

SUBMITTER: Ho LJ 

PROVIDER: S-EPMC8104424 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature