Increased risk of Alzheimer's disease among patients with age-related macular degeneration: A nationwide population-based study.

ABSTRACT:

Objective

This study aimed to investigate the risk of Alzheimer's disease among patients with age-related macular degeneration and its association with confounding comorbidities.

Method

This was a population-based, retrospective cohort study. By accessing data from the National Health Insurance Research Database of Taiwan, we identified 10,578 patients aged 50-100 years who were newly diagnosed with age-related macular degeneration between 2000 and 2012 and 10,578 non- age-related macular degeneration individuals. The comorbidities assessed were osteoporosis, diabetes, cirrhosis, cerebrovascular disease, chronic kidney disease, hypertension, hyperlipidemia, coronary artery disease, and chronic obstructive pulmonary disease.

Results

Patients with age-related macular de

SUBMITTER: Wen LY 

PROVIDER: S-EPMC8104445 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature