<i>Salmonella</i> Genomics and Population Analyses Reveal High Inter- and Intraserovar Diversity in Freshwater.

ABSTRACT: Freshwater can support the survival of the enteric pathogen Salmonella, though temporal Salmonella diversity in a large watershed has not been assessed. At 28 locations within the Susquehanna River basin, 10-liter samples were assessed in spring and summer over 2 years. Salmonella prevalence was 49%, and increased river discharge was the main driver of Salmonella presence. The amplicon-based sequencing tool, CRISPR-SeroSeq, was used to determine serovar population diversity and detected 25 different Salmonella serovars, including up to 10 serovars from a single water sample. On average, there were three serovars per sample, and 80% of Salmonella-positive samples contained more than one serovar. Serovars Give, Typhimurium, Thompson, and Infantis wer

SUBMITTER: Deaven AM 

PROVIDER: S-EPMC8104997 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature